tailieunhanh - báo cáo khoa học:" Health related quality of life after extremely preterm birth: a matched controlled cohort study"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Health related quality of life after extremely preterm birth: a matched controlled cohort study | Vederhus et al. Health and Quality of Life Outcomes 2010 8 53 http content 8 1 53 I HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access Heplth related quality of life after extremely preterm birth a matched controlled cohort study Bente J Vederhus 1 2 Trond Markestad1 3 Geir E Eide2 4 Marit Graue1 5 and Thomas Halvorsen1 3 Abstract Background The majority of infants born before the last trimester now grow up. However knowledge on subsequent health related quality of life HRQoL is scarce. We therefore aimed to compare HRQoL in children born extremely preterm with control children born at term. Furthermore we assessed HRQoL in relation to perinatal and neonatal morbidity and to current clinical and sociodemographic characteristics. Method The Child Health Questionnaire CHQ-PF50 and a general questionnaire were applied in a population based cohort of 10 year old children born at gestational age 28 weeks or with birth weight 1000 grams in Western Norway in 1991-92 and in term-born controls individually matched for gender and time of birth. The McNemar test and paired t-tests were used to explore group differences between preterms and matched controls. Paired regression models and analyses of interaction SPSS mixed linear model were used to explore potential effects of sociodemographic and clinical characteristics on HRQoL in the two groups. Results All 35 eligible preterm children participated. None had major impairments. Learning and or attention problems were present in 71 of preterms and 20 of controls odds ratio OR 95 confidence interval CI to . Insufficient professional support was described by 36 of preterm vs. 3 of control parents OR infinite CI to infinite . Preterms scored lower on eight CHQ-PF50 sub-scales and the two summary scores boys accounting for most of the deficits in areas of behavior psychosocial functioning and parental burden. HRQoL was associated with learning and or attention problems in both preterm and .