tailieunhanh - báo cáo khoa học:" The laval questionnaire: a new instrument to measure quality of life in morbid obesity"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: The laval questionnaire: a new instrument to measure quality of life in morbid obesity | Therrien et al. Health and Quality of Life Outcomes 2011 9 66 http content 9 1 66 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access The laval questionnaire a new instrument to measure quality of life in morbid obesity Fanny Therrien1 Picard Marceau Nathalie Turgeon Simon Biron Denis Richard and Yves Lacasse Abstract Background Our recent review of the literature uncovered eleven obesity-specific quality of life questionnaires all with incomplete demonstration of their measurement properties. Our objective was to validate a new selfadministered questionnaire specific to morbid obesity to be used in clinical trials. The study was carried out at the bariatric surgery clinic of Laval Hospital Quebec City Canada. Methods This study followed our description of health-related quality of life in morbid obesity from which we constructed the Laval Questionnaire. Its construct validity and responsiveness were tested by comparing the baseline and changes at 1-year follow-up in 6 domain scores symptoms activity mobility personal hygiene clothing emotions social interactions sexual life with those of questionnaires measuring related constructs SF-36 Impact of Weight on Quality of Life-Lite Rosenberg Self-Esteem Scale and Beck Depression Inventory-II . Results 112 patients 67 who got bariatric surgery 45 who remained on the waiting list during the study period participated in this study. The analysis of the discriminative function of the questionnaire showed moderate-to-high correlations between the scores in each domain of our instrument and the corresponding questionnaires. The analysis of its evaluative function showed 1 significant differences in score changes between patients with bariatric surgery and those without and 2 moderate-to-high correlations between the changes in scores in the new instrument and the changes in the corresponding questionnaires. Most of these correlations met the a priori predictions we had made regarding their direction and .