tailieunhanh - Special Topic: Endocrine Disruption

Understand the scientific basis of environmental endocrine disruption. • Explore the endocrine disruption hypothesis. • Review the classic case studies that have increased awareness in the public about environmental endocrine disruption. • Understand recent research and policy issues related to environmental endocrine disruption. • Explore the future pathways of analysis in the study of endocrine disruption. | Special Topic Endocrine Disruption Principles of Environmental Toxicology Instructor Gregory Möller . University of Idaho Principles of Environmental Toxicology Learning Objectives Understand the scientific basis of environmental endocrine disruption. Explore the endocrine disruption hypothesis. Review the classic case studies that have increased awareness in the public about environmental endocrine disruption. Understand recent research and policy issues related to environmental endocrine disruption. Explore the future pathways of analysis in the study of endocrine disruption. Principles of Environmental Toxicology Endocrine Disrupters Chemicals which interfere with endocrine system function. Endocrine system consists of glands and the hormones they produce. - Pituitary thyroid and adrenal glands the female ovaries and male testes. Hormones are biochemicals. - Produced by endocrine glands. - Travel through the bloodstream and cause responses in other parts of the body. Hormones of primary concern. - Estrogen androgen and thyroid hormones. Principles of Environmental Toxicology Endocrine Disrupters Principles of Environmental Toxicology Principles of Environmental Toxicology Video Fooling with Nature PBS Frontline Endocrine Disruption Observations Cryptorchidism in the Florida panther. Small baculum in young male otters. Small penises in alligators. Sex reversal in fish. Altered social behavior in birds. Proposed that EDCs also may have contributed to increases in testicular cancer and hypospadias and the reported decline in human sperm counts. Principles of Environmental Toxicology Example Antibiotic Soap Triclosan the common antiseptic was found in of the United States water resources surveyed USGS . A broad-spectrum antibacterial - antimicrobial agent classified as a Class III drug by the FDA. Bacteriostatic activity against a wide range of bacteria has lead to popular use in - Personal care products cosmetics anti- microbial creams acne treatment .

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