tailieunhanh - báo cáo khoa học:" The comparative burden of mild, moderate and severe Fibromyalgia: results from a cross-sectional survey in the United States"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: The comparative burden of mild, moderate and severe Fibromyalgia: results from a cross-sectional survey in the United States | Schaefer et al. Health and Quality of Life Outcomes 2011 9 71 http content 9 1 71 HEALTH AND QUALITY OF LIFE OUTCOMES RESEARCH Open Access The comparative burden of mild moderate and severe Fibromyalgia results from a cross-sectional survey in the United States 1 2 11 3 4 Caroline Schaefer Arthi Chandran Meghan Hufstader Rebecca Baik Michael McNett Don Goldenberg Robert Gerwin5 and Gergana Zlateva2 Abstract Background Fibromyalgia FM is characterized by chronic widespread pain fatigue and other symptoms yet few studies have comprehensively assessed its humanistic burden. This observational study evaluates the impact of FM severity on patients symptoms health-related quality of life HRQoL and productivity in the United States. Methods 203 FM subjects were recruited from 20 physician offices. Subjects completed a questionnaire including the EuroQol 5D EQ-5D Fibromyalgia Impact Questionnaire FIQ Multidimensional Assessment of Fatigue MAF Medical Outcomes Study Sleep Scale MOS-SS and Hospital Anxiety and Depression Scale HADS and questions about demographics pain and other symptoms HRQoL and productivity. FIQ total scores were used to define FM severity with 0- 39 39- 59 and 59-100 representing mild moderate and severe FM respectively. Sites recorded subjects clinical characteristics and FM treatment on case report forms using medical records. Summary statistics were calculated for continuous variables and frequency distributions for categorical variables. Differences across FM severity groups were evaluated using the Kruskal-Wallis or Chi-square tests. Statistical significance was evaluated at the level. Results Mean SD age was 95 were female. Most 92 were prescribed medication for FM 24 and 66 reported moderate and severe FM respectively. Mean SD scores were for pain intensity for EQ-5D for MAF for MOS-SS Sleep Problems Index for HADS anxiety and for HADS depression. Subjects with .