tailieunhanh - Báo cáo y học: " Pathophysiology of the systemic inflammatory response after major accidental trauma"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Pathophysiology of the systemic inflammatory response after major accidental trauma | Scandinavian Journal of Trauma Resuscitation and Emergency Medicine BioMed Central Open Access Review Pathophysiology of the systemic inflammatory response after major accidental trauma Anne Craveiro Brochner 1 2 and PalleToft1 2 Address Department of Anaesthesiology and Intensive Care Medicine Odense University Hospital Odense Denmark and institute of Clinical Research University of Southern Denmark Odense Denmark Email Anne Craveiro Brochner - Annecrbr@ Palle Toft - Corresponding author Published 15 September 2009 Received 29 April 2009 J- _Jr-__Accepted 15 September 2009 Scandinavian Journal of Trauma Resuscitation and Emergency Medicine 2009 17 43 doi l 757-7241-17-43 This article is available from http content 17 1Z43 2009 Brochner and Toft licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Background The purpose of the present study was to describe the pathophysiology of the systemic inflammatory response after major trauma and the timing of final reconstructive surgery. Methods An unsystematic review of the medical literature was performed and articles pertaining to the inflammatory response to trauma were obtained. The literature selected was based on the preference and clinical expertise of authors. Discussion The inflammatory response consists of hormonal metabolic and immunological components and the extent correlates with the magnitude of the tissue injury. After trauma and uncomplicated surgery a delicate balance between pro- and anti-inflammatory mediators is observed. Trauma patients are however often exposed not only to .