tailieunhanh - báo cáo khoa học:" Expression of caspase-3, p53 and Bcl-2 in generalized aggressive periodontitis"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Expression of caspase-3, p53 and Bcl-2 in generalized aggressive periodontitis | Head Face Medicine BioMed Central Research Open Access Expression of caspase-3 p53 and Bcl-2 in generalized aggressive periodontitis ule Bulut 1 Hilal Uslu1 B Handan Ozdemir2 and Omer Engin Bulut3 Address 1Baskent University Faculty of Dentistry Department of Periodontology Ankara Turkey 2Baskent University Faculty of Medicine Department of Pathology Ankara Turkey and 3Baskent University Faculty of Dentistry Department of Oral and Maxillofacial Surgery Ankara Turkey Email ule Bulut - Suleb@ Hilal Uslu - usluhilaladana@ B Handan Ozdemir - Handano@ Omer Engin Bulut - omerenginbulut@ Corresponding author Published 20 June 2006 Received 03 February 2006 Head Face Medicine 2006 2 17 doi 1746-160X-2-17 Accepted 20 June 2006 This article is available from http content 2 1 17 2006 Bulut et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Apoptosis or programmed cell death is a form of physiological cell death. It is increased or decreased in the presence of infection inflammation or tissue remodelling. Previous studies suggest that apoptosis is involved in the pathogenesis of inflammatory periodontal disease. The aim of the present study was to investigate the clinical features and known indicators of apoptosis p53 Bcl-2 Caspase-3 in patients with generalized aggressive periodontitis GAP Methods Eight patients with GAP who had sites with probing depths PD 5 mm and 10 periodontally-healthy persons were included in the study. Clinical examinations and PD were performed and the plaque index and gingival index were recorded. Gingival tissues biopsies were obtained from active site of each patient and from healthy individuals. The .