tailieunhanh - Báo cáo y học: " Osseous metaplasia in an ulcerating tubular adenoma of the colon: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Osseous metaplasia in an ulcerating tubular adenoma of the colon: a case report | Journal of Medical Case Reports BioMed Central Case report Open Access Osseous metaplasia in an ulcerating tubular adenoma of the colon a case report Victoria White1 Aidan G Shaw 2 Gillian M Tierney1 Jonathan N Lund2 and David Semeraro3 Address Department of Colorectal Surgery Derby City General Hospital Derby UK 2School of Graduate Medicine and Health University of Nottingham United Kingdom Derby DE22 3DT UK and 3Department of Histopathology Derby City General Hospital Derby UK Email Victoria White - mzyyvaw@ Aidan G Shaw - drshaw@ Gillian M Tierney - Jonathan N Lund - David Semeraro - Corresponding author Published 29 April 2008 Received 21 December 2007 Journal of Medical Case Reports 2008 2 130 doi 1752-1947-2-130 Accepted 29 April 2008 This article is available from http content 2 1 130 2008 White et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Heterotopic bone is rarely found in the gastrointestinal tract. Here we report a rare case of metaplastic ossification within a benign ulcerating adenoma and review the literature concerning the aetiology. Case presentation A 63-year-old woman who presented with a history of melaena was found at colonoscopy to have a pedunculated ulcerating polyp. Histological examination demonstrated multiple areas of osseous metaplasia within the polyp stroma. Conclusion Heterotopic ossification in colonic adenomas is a particularly rare phenomenon with the majority of cases occurring within malignant lesions. The suggested mechanisms for its aetiology still remain unclear. Introduction Heterotopic .