tailieunhanh - Báo cáo y học: " Atopic dermatitis, cutaneous steroids and cataracts in children: two case reports"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Atopic dermatitis, cutaneous steroids and cataracts in children: two case reports | Journal of Medical Case Reports BioMed Central Case report Open Access Atopic dermatitis cutaneous steroids and cataracts in children two case reports Andrew Tatham Address Leicester Royal Infirmary Infirmary Square Leicester LE1 5WW UK Email Andrew Tatham - andrewtatham@ Published 28 April 2008 Received 18 December 2007 Journal of Medical Case Reports 2008 2 124 doi 1752-1947-2-124 Accepted 28 April 2008 This article is available from http content 2 1 124 2008 Tatham licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Atopic dermatitis is a chronic pruritic eczematous skin disease mediated through an immediate type I hypersensitivity reaction. Posterior sub-capsular cataracts are a recognised complication of atopic dermatitis in adults however they are rare in children. The management of atopic dermatitis is based on the exclusion of allergens the use of emollients and on topical corticosteroids for disease exacerbations. Cataracts may be due to atopic dermatitis but may also occur secondary to the use of corticosteroids. Case presentation We describe two children with atopic dermatitis treated with cutaneous corticosteroids both of whom were diagnosed with bilateral posterior sub-capsular cataracts. Conclusion These cases demonstrate that atopic dermatitis and topical corticosteroids may be associated with cataracts in children as well as adults. The cause of cataracts in atopic dermatitis is not known however it has been suggested that habitual tapping and rubbing of the face may play a role. Care needs to be taken when prescribing corticosteroids. Inadequate treatment of atopic dermatitis may lead to other ocular complications such as keratitis and .