tailieunhanh - Báo cáo y học: "Developing a realistic sexual network model of chlamydia transmission in Britain"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Developing a realistic sexual network model of chlamydia transmission in Britain | Theoretical Biology and Medical Modelling Research Developing a realistic sexual network model of chlamydia transmission in Britain BioMed Central Open Access Katherine ME Turner 1 Elisabeth J Adams1 Nigel Gay1 Azra C Ghani2 Catherine Mercer3 and W John Edmunds1 Address 1Health Protection Agency Centre for Infections 61 Colindale Ave Colindale London NW9 5EQ UK 2London School of Hygiene Tropical Medicine Keppel Street London WC1E 7HT UK and 3Department of Primary Care and Population Sciences University College London Mortimer Market Centre Mortimer Market London WC1E 6AU UK Email Katherine ME Turner - Elisabeth J Adams - Nigel Gay - Azra C Ghani - Catherine Mercer - CMercer@ W John Edmunds - Corresponding author Published 20 January 2006 Received 09 November 2005 Theoretical Biology and Medical Modelling 2006 3 3 doi 1742-4682-3-3 Accepted 20 January 2006 This article is available from http content 3 1 3 2006 Turner et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background A national chlamydia screening programme is currently being rolled out in the UK and other countries. However much of the epidemiology remains poorly understood. In this paper we present a stochastic individual based dynamic sexual network model of chlamydia transmission and its parameterisation. Mathematical models provide a theoretical framework for understanding the key epidemiological features of chlamydia sexual behaviour health care seeking and transmission dynamics. Results The model parameters were estimated either directly or by systematic fitting to a variety of .

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