tailieunhanh - Báo cáo y học: " A comparative study of a theoretical neural net model with MEG data from epileptic patients and normal individuals"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: A comparative study of a theoretical neural net model with MEG data from epileptic patients and normal individuals | Theoretical Biology and Medical Modelling BioMed Central Research Open Access A comparative study of a theoretical neural net model with MEG data from epileptic patients and normal individuals A Kotini 1 P Anninos1 AN Anastasiadis1 and D Tamiolakis2 Address laboratory of Medical Physics Medical School Democritus University of Thrace University Campus Alex polis 68100 Greece and 2General Hospital of Chania Crete Greece Email A Kotini - akotin@ P Anninos - anninos@ AN Anastasiadis - achilleas@ D Tamiolakis - cyto@ Corresponding author Published 07 September 2005 Received 27 April 2005 Theoretical Biology and Medical Modelling 2005 2 37 doi 1742-4682-2-37 Accepted 07 September 2005 This article is available from http content 2 1 37 2005 Kotini et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Objective The aim of this study was to compare a theoretical neural net model with MEG data from epileptic patients and normal individuals. Methods Our experimental study population included 10 epilepsy sufferers and 10 healthy subjects. The recordings were obtained with a one-channel biomagnetometer SQUID in a magnetically shielded room. Results Using the method of x2-fitting it was found that the MEG amplitudes in epileptic patients and normal subjects had Poisson and Gauss distributions respectively. The Poisson connectivity derived from the theoretical neural model represents the state of epilepsy whereas the Gauss connectivity represents normal behavior. The MEG data obtained from epileptic areas had higher amplitudes than the MEG from normal regions and were comparable with the theoretical magnetic fields from Poisson and Gauss .