tailieunhanh - Báo cáo y học: " Mathematical model of blunt injury to the vascular wall via formation of rouleaux and changes in local hemodynamic and rheological factors. Implications for the mechanism of traumatic myocardial infarction"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Mathematical model of blunt injury to the vascular wall via formation of rouleaux and changes in local hemodynamic and rheological factors. Implications for the mechanism of traumatic myocardial infarction | Theoretical Biology and Medical Modelling BioMed Central Research Open Access Mathematical model of blunt injury to the vascular wall via formation of rouleaux and changes in local hemodynamic and rheological factors. Implications for the mechanism of traumatic myocardial infarction Rovshan M Ismailov Address Department of Epidemiology Graduate School of Public Health University of Pittsburgh Pittsburgh PA 15213 USA Email Rovshan M Ismailov - rovshani@ Corresponding author Published 30 March 2005 Received 16 January 2005 Theoretical Biology and Medical Modelling 2005 2 13 doi 1742-4682-2-13 Accepted 30 March 2005 This article is available from http content 2 1 13 2005 Ismailov licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Blood viscosity is fundamentally important in clinical practice yet the apparent viscosity at very low shear rates is not well understood. Various conditions such as blunt trauma may lead to the appearance of zones inside the vessel where shear stress equals zero. The aim of this research was to determine the blood viscosity and quantitative aspects of rouleau formation from erythrocytes at yield velocity and therefore shear stress equal to zero. Various fundamental differential equations and aspects of multiphase medium theory have been used. The equations were solved by a method of approximation. Experiments were conducted in an aerodynamic tube. Results The following were determined 1 The dependence of the viscosity of a mixture on volume fraction during sedimentation of a group of particles forming no aggregates confirmed by published experimental data on the volume fractions of the second phase f2 up to 2 The dependence of the viscosity of the