tailieunhanh - Báo cáo y học: "Malakoplakia of the appendix, an uncommon entity at an unusual site: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Malakoplakia of the appendix, an uncommon entity at an unusual site: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Malakoplakia of the appendix an uncommon entity at an unusual site a case report Sameer S Shaktawat 1 and Mark CJ Sissons2 Address Department of Histopathology Central Manchester and Manchester Children s University Hospital NHS Trust Oxford Road Manchester M13 9WL UK and 2Blackpool Victoria Hospital Whinney Heys Road Blackpool Lancashire FY3 8NR UK Email Sameer S Shaktawat - sameeroshni@ Mark CJ Sissons - Corresponding author Published 29 May 2008 Received 25 July 2007 Journal of Medical Case Reports 2008 2 181 doi 1752-1947-2-181 Accepted 29 May 2008 This article is available from http content 2 1 181 2008 Shaktawat and Sissons licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Malakoplakia is an uncommon inflammatory condition usually affecting the genitourinary tract which has been associated with infections tumours and immunocompromised states. Case presentation We report a case of malakoplakia in the appendix of a 61 -year-old man with a long-standing history of ulcerative colitis. Clinically and macroscopically malakoplakia can simulate tumours or abscesses and can cause diagnostic difficulties. Histologically malakoplakia in the gastrointestinal tract must be differentiated from Whipple disease other infectious and noninfectious granulomatous disorders and histiocyte storage diseases. To the best of our knowledge this is the first case of malakoplakia of the appendix reported in association with ulcerative colitis and the sixth reported case of malakoplakia of the appendix in the literature. Although the underlying disease in our case was ulcerative .