tailieunhanh - Báo cáo y học: " Nitrofurantoin-induced pulmonary fibrosis: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Nitrofurantoin-induced pulmonary fibrosis: a case report | Journal of Medical Case Reports BioMed Central Open Access Nitrofurantoin-induced pulmonary fibrosis a case report Natascha NT Goemaere1 Karin Grijm2 3 Peter ThW van Hal2 and Michael A den Bakker 1 Address 1Departmentof Pathology Josephine Nefkens Institute Erasmus MC - University Medical Center Rotterdam 3000 CA Rotterdam The Netherlands 2Department of Respiratory Medicine Josephine Nefkens Institute Erasmus MC - University Medical Center Rotterdam 3000 CA Rotterdam The Netherlands and 3Department of Respiratory Medicine Spaarne Ziekenhuis 2130 AT Hoofddorp The Netherlands Email Natascha NT Goemaere - Karin Grijm - KGrijm@ Peter ThW van Hal - Michael A den Bakker - Corresponding author Published 21 May 2008 Received 26 July 2007 Journal of Medical Case Reports 2008 2 169 doi 1752-1947-2-169 Accepted 21 May 2008 This article is available from http content 2 1 169 2008 Goemaere et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract__ Introduction Nitrofurantoin is a commonly used drug in the treatment and prevention of urinary tract infections. Many adverse effects of nitrofurantoin have been documented including aplastic anemia polyneuritis and liver and pulmonary toxicity. Case presentation We describe the clinical history and the autopsy findings in a 51-year-old woman with lung fibrosis of unknown etiology. She had a history of recurrent urinary tract infections treated with nitrofurantoin for many years. She was referred to our hospital for screening for lung transplantation because of severe .