tailieunhanh - Báo cáo y học: "Continuous glucose monitors prove highly accurate in critically ill children"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Continuous glucose monitors prove highly accurate in critically ill children. | Bridges et al. Critical Care 2010 14 R176 http content 14 5 R176 c CRITICAL CARE RESEARCH Open Access Continuous glucose monitors prove highly accurate in critically ill children DrAvs IV I D I r r I z t 2-r3r4 xx H IV I s L ft r 2 5 IV ỉ D Diz iL 2 3 Brian C Bridges Catherine M Preissig Kevin O Maher Mark R Rigby Abstract Introduction Hyperglycemia is associated with increased morbidity and mortality in critically ill patients and strict glycemic control has become standard care for adults. Recent studies have questioned the optimal targets for such management and reported increased rates of iatrogenic hypoglycemia in both critically ill children and adults. The ability to provide accurate real-time continuous glucose monitoring would improve the efficacy and safety of this practice in critically ill patients. The aim of our study is to determine if a continuous interstitial glucose monitor will correlate with blood glucose values in critically ill children. Methods We evaluated 50 critically ill children age 6 weeks to 16 years old with a commercially available continuous glucose monitor CGM Medtronic Guardian . CGM values and standard blood glucose BG values were compared. During the study no changes in patient management were made based on CGM readings alone. Results Forty-seven patients had analyzable CGM data. A total of 1 555 CGM and routine BG measurements were compared using Clarke error grid and Bland-Altman analysis. For all readings were within clinically acceptable agreement. The mean absolute relative difference between CGM and BG readings was . For the 1 555 paired CGM and BG measurements there is a statistically significant linear relationship between CGM values and BG P .0001 . A high degree of clinical agreement existed in three subpopulation analyses based on age illness severity and support measures. This included some of our smallest patients that is 12 months old those who required vasopressors and those who were treated