tailieunhanh - Báo cáo y học: "Surviving meningococcal septic shock in childhood: long-term overall outcome and the effect on health-related quality of life"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Surviving meningococcal septic shock in childhood: long-term overall outcome and the effect on health-related quality of life. | Buysse et al. Critical Care 2010 14 R124 http content 14 3 R124 RESEARCH Open Access Surviving meningococcal septic shock in childhood long-term overall outcome and the effect on health-related quality of life Corinne MP Buysse 1 Lindy CAC Vermunt2 Hein Raat3 Jan A Hazelzet1 Wim CJ Hop4 Elisabeth MWJ Utens2 and Koen FM Joosten1 Abstract Introduction The purpose of this study was to evaluate associations between long-term physical and psychological outcome variables in patients who survived meningococcal septic shock MSS in childhood. Methods The study population was made up of all MSS patients requiring intensive care treatment between 1988 and 2001. Results A total of 120 patients visited the follow-up clinic age at paediatric intensive care unit PICU admission years follow-up interval years age at follow-up years all medians . Four major outcomes were considered 1 major physical sequelae defined as major scars and or orthopaedic sequelae 29 120 2 mild neurological impairments 39 120 3 problem behaviour defined as a total score above the 90th percentile of the reference groups on questionnaires to screen for psychopathology 16 114 and 4 total intelligence quotient 85 18 115 . No differences were found between patients with major physical sequelae and patients without major physical sequelae as to the presence of problem behaviour or total IQ 85. Also no differences were found between patients with mild neurological impairments and patients without as to the presence of problem behaviour or total IQ 85. Finally no differences were found between patients with major physical sequelae and patients without as to the presence of mild neurological sequelae. Less favourable scores on behavioural and emotional problems were significantly associated with poorer health-related quality of life HR-QoL . HR-QoL scores were to a lesser amount predicted by severity of illness at time of PICU admission or by adverse physical outcome. Conclusions Long-term

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