tailieunhanh - Báo cáo y học: " Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection. | Gogos et al. Critical Care 2010 14 R96 http content 14 3 R96 c CRITICAL CARE RESEARCH Open Access Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection Charalambos Gogos1 Antigone Kotsaki2 Aimilia Pelekanou2 George Giannikopoulos3 Ilia Vaki2 Panagiota Maravitsa2 Stephanos Adamis4 Zoi Alexiou5 George Andrianopoulos6 Anastasia Antonopoulou2 Sofia Athanassia2 Fotini Baziaka2 Aikaterini Charalambous7 Sofia Christodoulou8 Ioanna Dimopoulou9 Ioannis Floros10 Efthymia Giannitsioti2 Panagiotis Gkanas11 Aikaterini Ioakeimidou12 Kyriaki Kanellakopoulou2 Niki Karabela12 Vassiliki Karagianni2 Ioannis Katsarolis2 Georgia Kontopithari9 Petros Kopterides9 Ioannis Koutelidakis13 Pantelis Koutoukas2 Hariklia Kranidioti2 Michalis Lignos9 Konstantinos Louis2 Korina Lymberopoulou14 Efstratios Mainas15 Androniki Marioli14 Charalambos Massouras2 Irini Mavrou9 Margarita Mpalla7 Martha Michalia16 Heleni Mylona17 Vassilios Mytas4 Ilias Papanikolaou17 Konstantinos Papanikolaou18 Maria Patrani12 Ioannis Perdios8 Diamantis Plachouras2 Aikaterini Pistiki2 Konstantinos Protopapas2 Kalliopi Rigaki12 Vissaria Sakka2 Monika Sartzi5 Vassilios Skouras18 Maria Souli2 Aikaterini Spyridaki2 Ioannis Strouvalis18 Thomas Tsaganos2 George Zografos19 Konstantinos Mandragos12 Phylis Klouva-Molyvdas16 Nina Maggina15 Helen Giamarellou2 Apostolos Armaganidis9 and Evangelos J Giamarellos-Bourboulis 2 Abstract Introduction Although major changes of the immune system have been described in sepsis it has never been studied whether these may differ in relation to the type of underlying infection or not. This was studied for the first time. Methods The statuses of the innate and adaptive immune systems were prospectively compared in 505 patients. Whole blood was sampled within less than 24 hours of advent of sepsis white blood cells were stained with monoclonal antibodies and analyzed though a flow cytometer. Results Expression of HLA-DR was .