tailieunhanh - Báo cáo y học: " Clinical features of H1N1 2009 infection in critically ill immunocompromised patients"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Clinical features of H1N1 2009 infection in critically ill immunocompromised patients. | Camous et al. Critical Care 2010 14 139 http content 14 2 139 CRITICAL CARE COMMENTARY L__ Clinical features of H1N1 2009 infection in critically ill immunocompromised patients I 2 1 iront 2mm ic1 2 irmnio I omĨ2lo1 2 Pmm2t2i lol 2no1 1 2 AHlino M2v1 2 r 2 i d 7 l2t2Cj 1 2 I o CThff2 3 Ldurei It Ca inuib vir gil lieLei I lidle fEiiniidiiuci Ca Het Adelii leividx DdviusLiiiieii jciomcLc Go 11 Antoine Rdbbdt4 Benoit Schleimer 1-2 dnd Élie Azoildy 1-2 Abstract Sedsondl influenzd virus hds been described ds dn emerging dnd severe pdthogen in immunocompromised hosts. Since the beginning of the 2009 inflienzd A novel H1N1 pdndemic severdl series hdve described the clinicdl course of the disedse in vdrious populdtions. We report the clinicdl course of H1N1 2009 infection in 10 immunocompromised pdtients. Hdlf of the pdtients received long-term steroid therapy. Disedse wds chdrdcterized by d clinicdl picture simildr to thdt of non-immunocompromised pdtients but with prolonged course dnd higher mortdlity. Infection is a major source of morbidity and the leading cause of death in immunocompromised patients 1 . The increased susceptibility to infection results from the intertwined effects of the immunocompromising condition treatments and co-morbidities 1 . Human infection with the novel H1N1 influenza virus was first recognized in early April 2009 and declared a worldwide pandemic by the World Health Organization in June 2009. Recent case series provide information on the clinical course risk factors and outcome of H1N1 v infection 2-4 . Both New Zealand and Canada have experienced H1N1 v outbreaks with severe illness requiring intensive care unit ICU admission ventilatory support and rescue therapies. However no case series have specifically described the features of H1NI v infection in immunocompromised patients. Here we report the clinical and epidemiologic features in 10 critically ill immunocompromised patients with H1N1 v infection. Correspondence