tailieunhanh - Báo cáo y học: "Goal-directed intraoperative therapy based on autocalibrated arterial pressure waveform analysis reduces hospital stay in high-risk surgical patients: a randomized, controlled trial"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Goal-directed intraoperative therapy based on autocalibrated arterial pressure waveform analysis reduces hospital stay in high-risk surgical patients: a randomized, controlled trial. | Mayer et al. Critical Care 2010 14 R18 http content 14 1 R18 c CRITICAL CARE RESEARCH Open Access Goal-directed intraoperative therapy based on autocalibrated arterial pressure waveform analysis reduces hospital stay in high-risk surgical patients a randomized controlled trial Jochen Mayer Joachim Boldt Andinet M Mengistu Kerstin D Rohm Stefan Suttner Abstract Introduction Several studies have shown that goal-directed hemodynamic and fluid optimization may result in improved outcome. However the methods used were either invasive or had other limitations. The aim of this study was to perform intraoperative goal-directed therapy with a minimally invasive easy to use device FloTrac Vigileo and to evaluate possible improvements in patient outcome determined by the duration of hospital stay and the incidence of complications compared to a standard management protocol. Methods In this randomized controlled trial 60 high-risk patients scheduled for major abdominal surgery were included. Patients were allocated into either an enhanced hemodynamic monitoring group using a cardiac index based intraoperative optimization protocol FloTrac Vigileo device GDT-group n 30 or a standard management group Control-group n 30 based on standard monitoring data. Results The median duration of hospital stay was significantly reduced in the GDT-group with 15 12 - days versus 19 14 - days P and fewer patients developed complications than in the Control-group 6 patients 20 versus 15 patients 50 P . The total number of complications was reduced in the GDT-group 17 versus 49 complications P . Conclusions In high-risk patients undergoing major abdominal surgery implementation of an intraoperative goal-directed hemodynamic optimization protocol using the FloTrac Vigileo device was associated with a reduced length of hospital stay and a lower incidence of complications compared to a standard management protocol. Trial Registration Clinical trial .