tailieunhanh - Báo cáo y học: "Complications of continuous renal replacement therapy in children: are all created equal"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Complications of continuous renal replacement therapy in children: are all created equal? | Palmieri Critical Care 2010 14 105 http content 14 1 105 CRITICAL CARE COMMENTARY L__ Complications of continuous renal replacement therapy in children are all created equal Tina L Palmieri See related research by Santiago etal. http content 13 6 R184 Abstract Continuous renal replacement therapy CRRT in pediatric acute kidney dysfunction has evolved in recent decades however little objective data exist for complications associated with CRRT. Santiago and colleagues are among the first to document four complications of acute kidney dysfunction in critically ill children catheterization-related insertion complications hypotension hemorrhage and electrolyte disturbances. They reported that hypotension at connection and electrolyte disturbance were the leading complications. Although this study is limited by small sample size and the outcome variables measured it is an important first step in assessing outcomes of CRRT in children. A prospective multicenter randomized trial will be needed to fully delineate the complications and define the risk benefit ratio of CRRT in children. The treatment of acute kidney dysfunction in critically ill children has advanced markedly in the past several decades. Currently continuous renal replacement therapy CRRT and peritoneal dialysis form the mainstays of treatment. However there is little objective information on patient outcomes and complications associated with CRRT. Santiago and colleagues 1 have taken the initiative to study CRRT complications and the factors contributing to those complications in 174 critically ill children treated from January 1996 to June 2009 at a single pediatric intensive care unit. Complications associated with catheterization hypotension at the time of CRRT connection hemorrhage and electrolyte disturbance in the first 72 hours were analyzed. The authors conclude that hypotension and electrolyte disturbances are the most common CRRT complications in children.