tailieunhanh - Báo cáo y học: " Sebaceous carcinoma of the skin of the breast: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Sebaceous carcinoma of the skin of the breast: a case report | Journal of Medical Case Reports BioMed Central Open Access Sebaceous carcinoma of the skin of the breast a case report Ahmed Alzaraa 1 Imran Ghafoor1 Andrew Yates2 and Alhad Dhebri1 Address Department of General Surgery Tameside General Hospital Manchester UK and 2Department of Histopathology Tameside General Hospital Manchester UK Email Ahmed Alzaraa - ahmedwahabf@ Imran Ghafoor - immyg21@ Andrew Yates - Alhad Dhebri - Corresponding author Published 15 August 2008 Received 2 February 2008 Journal of Medical Case Reports 2008 2 276 doi 1752-1947-2-276 Accepted 15 August 2008 This article is available from http content 2 1 276 2008 Alzaraa et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Sebaceous gland tumours are rare and their presence should be considered as a marker for Muir-Torre Syndrome alerting to search for an occult malignancy. Case presentation A 43-year-old Caucasian female patient underwent excision of a sebaceous cyst. Histopathology confirmed a sebaceous carcinoma. Further investigations revealed multiple intra-abdominal malignancies. She has been under regular follow-up in the relevant clinics. Conclusion Sebaceous carcinoma should be excised completely and followed-up for the detection of possible metastases. Surgical removal of primary or metastatic cancers may be curative and should be attempted wherever possible. It is very important for clinicians not to miss such skin lesions as they may precede the presentation of internal malignancies. Introduction Muir-Torre Syndrome MTS is defined by the combination of a sebaceous gland tumour and at least one visceral carcinoma .