tailieunhanh - Particle Toxicology - Chapter 21

Những năm gần đây đã chứng kiến sự tăng trưởng chưa từng có nghiên cứu và ứng dụng trong lĩnh vực khoa học nano và công nghệ nano. Có gia tăng sự lạc quan rằng công nghệ nano, áp dụng cho y học, sẽ mang lại những tiến bộ quan trọng trong chẩn đoán và điều trị bệnh. | 21 Nanoparticles in Medicine Paul J. A. Borm Centre of Expertise in Life Sciences Hogeschool Zuyd Detlef Muller-Schulte Magnamedics GmbH CONTENTS Particles in Nanomedicine Health Benefits and Imaging and Diagnostic Magnetic Fluorescent Quantum Nanomaterials and Nanodevices .392 Drug Delivery Dendrimers .397 Fullerenes .398 Polymer Magnetic Hazards and Risks of General Toxicological Effects of Effects on Blood and Cardiovascular Uptake and Effects of Nanoparticles in the Current Data on the Toxicology of Engineered Quantum Carbon Dendrimers .404 Wear Particles from Nanomaterials in Medicine Future Toxicological INTRODUCTION Recent years have witnessed unprecedented growth of research and applications in the area of nanoscience and nanotechnology. There is increasing optimism that nanotechnology as applied to medicine will bring significant advances in the diagnosis and treatment of disease. Anticipated 387 2007 by Taylor Francis Group LLC 388 Particle Toxicology applications in medicine include drug delivery diagnostics nutraceuticals and production of biocompatible materials ESF 2005 Ferrari 2005 Vision Paper 2005 . Engineered nanoparticles 100nm or nanostructured materials NSM are important tools to realize these applications. The reason why these nanoparticles NP are attractive for such purposes is based on their important and unique features such as their surface to mass ratio that is much larger than that of other particles their .