tailieunhanh - Báo cáo y học: " Pulmonary talc granulomatosis mimicking malignant disease 30 years after last exposure: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Pulmonary talc granulomatosis mimicking malignant disease 30 years after last exposure: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Pulmonary talc granulomatosis mimicking malignant disease 30 years after last exposure a case report William S Krimsky1 2 3 and Suneel Dhand 2 Address Johns Hopkins University School of Medicine Baltimore MD USA 2Franklin Square Hospital Center Baltimore MD USA and 3The Delmarva Foundation for Medical Care Cambridge MA USA Email William S Krimsky-krimskyw@ Suneel Dhand - suneeldhand@ Corresponding author Published 3 July 2008 Received 17 November 2007 Journal of Medical Case Reports 2008 2 225 doi 1752-1947-2-225 Accepted 3 July 2008 This article is available from http content 2 1 225 2008 Krimsky and Dhand licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Pulmonary talc granulomatosis is a rare disorder characterized by the development of foreign body granuloma secondary to talc exposure. Previous case reports have documented the illness in current intravenous drug users who inject medications intended for oral use. We present a rare case of the disease in a patient with a distant history of heroin abuse who presented initially with history and imaging findings highly suggestive of malignancy. Case presentation A 53-year-old man reported a 4-month history of increasing dyspnea and weight loss. He had a long history of smoking and admission chest X-ray revealed a density in the right hemithorax. Computed tomography confirmed a probable mass with further speculated opacities in both lung fields suspicious for malignant spread. Biopsies obtained using endobronchial ultrasound-guided aspiration returned negative for malignancy and showed bronchial epithelial cells with foreign body .