tailieunhanh - Báo cáo y học: " Effect of cardiopulmonary bypass on activated partial thromboplastin time waveform analysis, serum procalcitonin and C-reactive protein concentrations"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Effect of cardiopulmonary bypass on activated partial thromboplastin time waveform analysis, serum procalcitonin and C-reactive protein concentrations. | Available online http content 13 6 R180 Research Effect of cardiopulmonary bypass on activated partial thromboplastin time waveform analysis serum procalcitonin and C-reactive protein concentrations Bertrand Delannoy1 Marie-Laurence Guye1 Davy Hay Slaiman1 Jean-Jacques Lehot1 and Maxime Cannesson2 Department of Anesthesiology and Intensive Care Hospices Civils de Lyon Louis Pradel Hospital Claude Bernard Lyon 1 university ERI 22 28 avenue du doyen Lepine 69500 Bron France department of Anesthesiology Perioperative Care School of Medicine University of California Irvine 333 City Boulevard West Side Orange CA 92868-3301 USA Corresponding author Maxime Cannesson mcanness@ Received 14 Aug 2009 Revisions requested 28 Oct 2009 Revisions received 29 Oct 2009 Accepted 13 Nov 2009 Published 13 Nov 2009 Critical Care 2009 13 R180 doi cc8166 This article is online at http content 13 6 R1 80 2009 Delannoy et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Systemic inflammatory response syndrome SIRS is a frequent condition after cardiopulmonary bypass CPB and makes conventional biological tests fail to detect postoperative sepsis. Biphasic waveform BPW analysis is a new biological test derived from activated partial thromboplastin time that has recently been proposed for sepsis diagnosis. The aim of this study was to investigate the accuracy of BPW to detect sepsis after cardiac surgery under CPB. Methods We conducted a prospective study in American Society of Anesthesiologists ASA physical status III and IV patients referred for cardiac surgery under CPB. Procalcitonin PCT and BPW were recorded before surgery and every day during the first week following .