tailieunhanh - Báo cáo y học: "A pilot study for augmenting atomoxetine with methylphenidate: safety of concomitant therapy in children with attention-deficit/hyperactivity disorder"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: A pilot study for augmenting atomoxetine with methylphenidate: safety of concomitant therapy in children with attention-deficit/hyperactivity disorder. | Child and Adolescent Psychiatry and Mental Health BioMed Central Research A pilot study for augmenting atomoxetine with methylphenidate safety of concomitant therapy in children with attention-deficit hyperactivity disorder Gabrielle A Carlson 1 David Dunn2 Douglas Kelsey3 Dustin Ruff3 Susan Ball3 Lisa Ahrbecker3 and Albert J Allen3 Open Access Address Department of Child and Adolescent Psychiatry Stony Brook School of Medicine Stony Brook New York 11794-8790 USA 2Department of Psychiatry Indiana University School of Medicine Indianapolis Indiana 46202 USA and 3Lilly Research Laboratories Eli Lilly and Company Indianapolis Indiana 46268 USA Email Gabrielle A Carlson - David Dunn - ddunn@ Douglas Kelsey-kelsey_douglas_k@ Dustin Ruff - ruff_dustin@ Susan Ball - ballsg@ Lisa Ahrbecker - Albert J Allen - allenaj@ Corresponding author Published 27 September 2007 Received 20 February 2007 Child and Adolescent Psychiatry and Mental Health 2007 1 10 doi 1753-2000-1- Accepted 27 September 2007 10 This article is available from http content 1 1 10 2007 Carlson et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background This study examined augmenting atomoxetine with extended-release methylphenidate in children whose attention-deficit hyperactivity disorder ADHD previously failed to respond adequately to stimulant medication. Methods Children with ADHD and prior stimulant treatment N 25 received atomoxetine mg kg day plus placebo. After 4 weeks patients who were responders n 4 were continued on atomoxetine placebo while remaining patients were randomly assigned to either methylphenidate ATX MPH .