tailieunhanh - Báo cáo hóa học: " Hydroxyapatite Mineralization on the Calcium Chloride Blended Polyurethane Nanofiber via Biomimetic Method"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành hóa học dành cho các bạn yêu hóa học tham khảo đề tài: Hydroxyapatite Mineralization on the Calcium Chloride Blended Polyurethane Nanofiber via Biomimetic Method | Nirmala et al. Nanoscale Res Lett 2011 6 2 http content 6 1 2 o Nanoscale Research Letters a SpringerOpen Journal NANO EXPRESS Open Access Hydroxyapatite Mineralization on the Calcium Chloride Blended Polyurethane Nanofiber via Biomimetic Method 12 3 2 2 R Nirmala Ki Taek Nam R Navamathavan Soo-Jin Park Hak Yong Kim Abstract Polyurethane nanofibers containing calcium chloride CaCl2 were prepared via an electrospinning technique for the biomedical applications. Polyurethane nanofibers with different concentration of CaCl2 were electrospun and their bioactivity evaluation was conducted by incubating in biomimetic simulated body fluid SBF solution. The morphology structure and thermal properties of the polyurethane CaCl2 composite nanofibers were characterized by means of scanning electron microscopy SEM field-emission scanning electron microscopy energy dispersive X-ray spectroscopy X-ray diffraction Fourier transform infrared spectroscopy and thermogravimetry. SEM images revealed that the CaCl2 salt incorporated homogeneously to form well-oriented nanofibers with smooth surface and uniform diameters along their lengths. The SBF incubation test confirmed the formation of apatite-like materials exhibiting enhanced bioactive behavior of the polyurethane CaCl2 composite nanofibers. This study demonstrated that the electrospun polyurethane containing CaCl2 composite nanofibers enhanced the in vitro bioactivity and supports the growth of apatite-like materials. Introduction Electrospinning of biologically significant polymers has increased dramatically since the electrospun membranes were identified as a candidate for guided tissue regeneration applications 1-4 . In particular polyurethane is a thermoplastic biodegradable biocompatible polymer with excellent mechanical and physical properties 5 6 . Due to these merits polyurethane nanofibers have been found to be a very promising material of interest. It has been already reported that the .