tailieunhanh - báo cáo khoa học: " Solitary submucous neurofibroma of the mandible: review of the literature and report of a rare case"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Solitary submucous neurofibroma of the mandible: review of the literature and report of a rare case | Head Face Medicine BioMed Central Open Access Review Solitary submucous neurofibroma of the mandible review of the literature and report of a rare case Rita Depprich1 Daman D Singh 1 Petra Reinecke2 Norbert R Kubler1 and Jorg Handschel1 Address Department for Cranio- and Maxillofacial Surgery Heinrich-Heine-University Moorenstr. 5 D-40225 Dusseldorf Germany and 2Department for Pathology Heinrich-Heine-University Moorenstr. 5 D-40225 Dusseldorf Germany Email Rita Depprich - depprich@ Daman D Singh - Petra Reinecke - reinecke@ Norbert R Kubler - Jorg Handschel - handschel@ Corresponding author Published 13 November 2009 Head Face Medicine 2009 5 24 doi 1746-160X-5-24 Received 23 September 2009 Accepted 13 November 2009 This article is available from http content 5 1 24 2009 Depprich et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Solitary neurofibroma is a rare benign non-odontogenic tumor. Particularly in the oral cavity neurogenic tumors are rare especially if they are malignant. Neurofibromas may present either as solitary lesions or as part of the generalised syndrome of neurofibromatosis or von Recklinghausen s disease of the skin. Clinically oral neurofibromas usually appear as pediculated or sessile nodules with slow growth and mostly without pain. The diagnosis can be confirmed by histological examination. Neurofibromas are immunopositive for the S-100 protein indicating its neural origin. Treatment is surgical and the prognosis is excellent. For illustration