tailieunhanh - báo cáo khoa học: " Evaluation of herbal cannabis characteristics by medical users: a randomized trial"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Evaluation of herbal cannabis characteristics by medical users: a randomized trial | Harm Reduction Journal BioMed Central Research Evaluation of herbal cannabis characteristics by medical users a randomized trial Mark A Ware 1 Thierry Ducruet2 and Ann R Robinson2 Open Access Address Departments of Anesthesia and Family Medicine McGill University Montreal Quebec Canada and 2Boreal Primum Inc. 913 Cherrier Montreal Quebec Canada Email Mark A Ware - Thierry Ducruet - Ann R Robinson - Corresponding author Published 13 November 2006 Received 15 August 2006 __ AA J .lAiio iunTrnm Accepted 13 November 2006 Harm Reduction Journal 2006 3 32 doi l477-75l7-3-32 This article is available from http content 3 l 32 2006 Ware et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Cannabis in herbal form is widely used as self-medication by patients with diseases such as HIV AIDS and multiple sclerosis suffering from symptoms including pain muscle spasticity stress and insomnia. Valid clinical studies of herbal cannabis require a product which is acceptable to patients in order to maximize adherence to study protocols. Methods We conducted a randomized controlled crossover trial of 4 different herbal cannabis preparations among 8 experienced and authorized cannabis users with chronic pain. Preparations were varied with respect to grind size THC content and humidity. Subjects received each preparation on a separate day and prepared the drug in their usual way in a dedicated and licensed clinical facility. They were asked to evaluate the products based on appearance smell colour humidity grind size ease of preparation and overall appearance and smoking characteristics burn .