tailieunhanh - báo cáo khoa học: " Therapeutic challenges in hepatitis C-infected injection drug using patients"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Therapeutic challenges in hepatitis C-infected injection drug using patients | Harm Reduction Journal BioMed Central Review Open Access Therapeutic challenges in hepatitis C-infected injection drug using patients Curtis L Cooper 1 2 and Edward J Mills2 3 Address 1Associate Professor of Medicine-University of Ottawa Hospital Division of Infectious Diseases-The Ottawa Hospital Ottawa Canada 2Centre for International Health and Human Rights Studies Toronto Canada and 3Faculty of Health Sciences Clinical Epidemiology and Biostatistics McMaster University Hamilton Canada Email Curtis L Cooper - ccooper@ Edward J Mills - EMILLS@ Corresponding author Published 10 November 2006 Received 05 August 2006 Accepted 10 November 2006 Harm Reduction Journal 2006 3 31 doi 1477-7517-3-31 This article is available from http content 3 1 31 2006 Cooper and Mills licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Hepatitis C Viral HCV infection in the injection drug user IDU population is a major medical concern. Concurrent substance abuse co-morbid mental health conditions poor socioeconomic status and a complex treatment protocol that is often incompatible with the life styles of IDUs combine to account for poor uptake and completion of HCV treatment. This article discusses HCV antiviral treatment issues relevant to IDUs chronically infected with this virus. The effect of non-injected substances of abuse on treatment outcome is considered. Priority issues requiring research are discussed. Background Given its high incidence and prevalence the complications of chronic hepatitis C virus HCV infection will impact the morbidity and mortality of at-risk populations in the developed world for the foreseeable future 1 . Those with substance abuse concerns .

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