tailieunhanh - UNDERSTANDING TUBERCULOSIS – ANALYZING THE ORIGIN OF MYCOBACTERIUM TUBERCULOSIS PATHOGENICITY

Vitamin C can be transported into the cell either as its reduced form or dehydroascorbate (oxidized form), using active sodium-dependent transporters (SVCT1 and SVCT2) and facilitative glucose transporters (GLUTs) (André et al., 2010). GLUTs also permit the permeation of vitamin C into mitochondria. Besides the protective role of vitamin C against oxidative injury within the cytosol, this water-soluble nutrient can also confer protection to mitochondria that are targets of oxidative attacks resulting from ROS produced as a side product of the respiratory chain that is active within mitochondria. Several beneficial functions have been attributed to vitamin C, . as. | UNDERSTANDING TUBERCULOSIS -ANALYZING THE ORIGIN OF MYCOBACTERIUM TUBERCULOSIS PATHOGENICITY Edited by Pere-Joan Cardona Understanding Tuberculosis - Analyzing the Origin of Mycobacterium Tuberculosis Pathogenicity Edited by Pere-Joan Cardona Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Marija Radja Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published February 2012 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Understanding Tuberculosis - Analyzing the Origin of .

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