tailieunhanh - TARGETING NEW PATHWAYS AND CELL DEATH IN BREAST CANCER

Carotenoids are hydrophobic compounds and thereby act as lipophilic antioxidants preventing polyunsaturated fatty acids from oxidative damages. In fact, carotenoids are incorporated into lipid membranes and thus could act as chain-breaking antioxidants by stopping free radical chain reactions (propagation of lipid peroxidation), scavenging lipid peroxyl radicals (LOO•), avoiding the abstraction of allylic hydrogens from neighboring lipids. Inactivation of lipoxygenase activity by carotenoids is also proposed as another mechanism of protection against oxidative stress. Although it is still controversial, it has been debated that vitamin E regenerates the radical form of cartenoids and vice versa (Palace et al., 1999; Mortensen et. | TARGETING NEW PATHWAYS AND CELL DEATH IN BREAST CANCER Edited by Rebecca L. Aft Targeting New Pathways and Cell Death in Breast Cancer Edited by Rebecca L. Aft Published by InTech Janeza Trdine 9 51000 Rijeka Croatia Copyright 2012 InTech All chapters are Open Access distributed under the Creative Commons Attribution license which allows users to download copy and build upon published articles even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. After this work has been published by InTech authors have the right to republish it in whole or part in any publication of which they are the author and to make other personal use of the work. Any republication referencing or personal use of the work must explicitly identify the original source. As for readers this license allows users to download copy and build upon published chapters even for commercial purposes as long as the author and publisher are properly credited which ensures maximum dissemination and a wider impact of our publications. Notice Statements and opinions expressed in the chapters are these of the individual contributors and not necessarily those of the editors or publisher. No responsibility is accepted for the accuracy of information contained in the published chapters. The publisher assumes no responsibility for any damage or injury to persons or property arising out of the use of any materials instructions methods or ideas contained in the book. Publishing Process Manager Silvia Vlase Technical Editor Teodora Smiljanic Cover Designer InTech Design Team First published February 2012 Printed in Croatia A free online edition of this book is available at Additional hard copies can be obtained from orders@ Targeting New Pathways and Cell Death in Breast Cancer Edited by Rebecca L. Aft p. cm. ISBN 978-953-51-0145-1 INTECH open science I open minds

• Y học thường thức
• GMO Risk Assessments
• Improving Future
• Assessment Analyses
• Breast Cancer
• Post Genomic Era
• Genomics Data
• Nutritional Health
• Feeding and Fluids
• Premature and Sick Newborn
• Prostate Cancer