tailieunhanh - Báo cáo y học: " Sensorineural hearing loss in Lassa fever: two case reports"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Sensorineural hearing loss in Lassa fever: two case reports | Journal of Medical Case Reports BioMed Central Open Access Sensorineural hearing loss in Lassa fever two case reports Peter O Okokhere1 Titus S Ibekwe 2 and George O Akpede3 Address Department of Medicine Irrua Specialist Teaching Hospital Irrua Nigeria 2ENT Division Department of Surgery Irrua Specialist Teaching Hospital Irrua Nigeria and 3Department of Pediatrics Irrua Specialist Teaching Hospital Irrua Nigeria Email Peter O Okokhere - pitaokokhere@ Titus S Ibekwe - ibekwets@ George O Akpede - akpedeg@ Corresponding author Published 29 January 2009 Received 17 September 2008 Journal of Medical Case Reports 2009 3 36 doi 1752-1947-3-36 Accepted 29 January 2009 This article is available from http content 3 l 36 2009 Okokhere et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract_ Introduction Lassa fever is an acute arena viral haemorrhagic fever with varied neurological sequelae. Sensorineural hearing loss is one of the rare complications which occur usually during the convalescent stage of the infection. Case presentation The cases of two female patients aged 19 and 43 years old respectively with clinical features suggestive of Lassa fever and confirmed by immunoserological Lassa-virus-specific reverse transcriptase polymerase chain reaction are presented. Both patients developed severe sensorineural hearing loss at acute phases of the infections. Conclusion Sensorineural hearing loss from Lassa fever infections can occur in both acute and convalescent stages and is probably induced by an immune response. Introduction Lassa fever is an acute arena viral haemorrhagic fever