tailieunhanh - Báo cáo y học: " Oral melanoacanthoma: a case report and review of the literature"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Oral melanoacanthoma: a case report and review of the literature | Journal of Medical Case Reports BioMed Central Open Access Case report Oral melanoacanthoma a case report and review of the literature Vidya Lakshminarayanan and Kannan Ranganathan Address Department of Oral and Maxillofacial Pathology Ragas Dental College and Hospital East Coast Road Chennai Tamilnadu 600119 India Email Vidya Lakshminarayanan - akavidya@ Kannan Ranganathan - Corresponding author Published 13 January 2009 Received I February 2008 Journal of Medical Case Reports 2009 3 11 doi 1752-1947-3-11 Accepted 13 January 2009 This article is available from http content 3 I II 2009 Lakshminarayanan and Ranganathan licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Oral melanoacanthoma is a rare benign pigmented lesion characterized clinically by the sudden appearance and rapid growth of a macular brown-black lesion and histologically by acanthosis of the superficial epithelium and proliferation of dendritic melanocytes. Case presentation We present a case report of oral melanoacanthoma in a 24-year-old Asian Indian man. He presented with an intra-oral brown macular lesion on the left buccal mucosa with a duration of one and a half months. Microscopic examination revealed acanthosis of stratified squamous surface epithelium and dendritic melanocytes diffusely distributed in the epithelium the Masson-Fontana silver impregnation technique was used to demonstrate the dendritic melanocytes. Based on the history clinical features and histological presentation the lesion was diagnosed as melanoacanthoma. Conclusion This is the first reported instance of oral melanoacanthoma in the Indian subcontinent. This report details the course of the