tailieunhanh - Báo cáo y học: " Graft-versus-lymphoma effect in a 64-year-old caucasian woman after allogeneic stem-cell transplantation: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Graft-versus-lymphoma effect in a 64-year-old caucasian woman after allogeneic stem-cell transplantation: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Graft-versus-lymphoma effect in a 64-year-old Caucasian woman after allogeneic stem-cell transplantation a case report Gerhard Behre f Thomas Weber Sebastian Theurich and Maximilian ChristopeiC Address Department of Internal Medicine IV Oncology and Hematology Martin-Luther-University Halle-Wittenberg Ernst-Grube-Str. 40 D06097 Halle Germany Email Gerhard Behre - Thomas Weber - Sebastian Theurich - Maximilian Christopeit - Corresponding author fEqual contributors Published 13 January 2009 Received 14 April 2008 Journal of Medical Case Reports 2009 3 10 doi 1752-1947-3-10 Accepted 13 January 2009 This article is available from http content 3 1 10 2009 Behre et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction The existence of a graft-versus-lymphoma effect is well established. When lacking a firm diagnosis however the clinician is challenged to to weigh the potential benefits of the graft-versus-lymphoma effect against potential dangers of graft-versus-host disease as well as against generalized viral infections. Case presentation We present evidence for a graft-versus-lymphoma effect in a 64-year-old caucasian woman with a transplanted peripheral blood-stem-cell graft from her Human Leukocyte Antigen-identical sister and propose diagnostic measures to distinguish between graft-versus-host effect and against viral disease or drug-induced reactions. Conclusion We were able to identify an allogeneic graft-reaction against progressive lymphoma .