tailieunhanh - Báo cáo y học: " Single lesion multibacillary leprosy, a treatment enigma: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Single lesion multibacillary leprosy, a treatment enigma: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Single lesion multibacillary leprosy a treatment enigma a case report Bishwa R Sapkota Kapil D Neupane and Ram K Maharjan Address Mycobacterial Research Laboratory Anandaban Hospital GPO Box 151 Kathmandu Nepal Email Bishwa R Sapkota - bishwasapkota@ Kapil D Neupane - lab@ Ram K Maharjan - anandaban@ Corresponding author Published 13 January 2009 Received 16 July 2008 Journal of Medical Case Reports 2009 3 8 doi 1752-1947-3-8 Accepted 13 January 2009 This article is available from http content 3 1 8 2009 Sapkota et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Leprosy exhibits a wide spectrum of presentation varying from the tuberculoid to the lepromatous pole with immunologically unstable borderline forms in-between depending upon the immune status of the individual. The clinical system of classification for the purpose of treatment includes the number of skin lesions and nerves involved as the basis for classifying the patients into multibacillary and paucibacillary. Case presentation A 20-year-old man belonging to a moderately endemic leprosy area in the Terai region of Nepal reported a large single hypopigmented well defined anaesthetic lesion on his left thigh extending to his knee which had been present for 2 years. There was no other nerve involvement. Clinical diagnosis was tuberculoid leprosy and immunological lateral flow test for antiPhenolic glycolipid-I antibody was positive. Six months of paucibacillary multidrug treatment was advised immediately. However the patient was reclassified as multibacillary on the basis of a positive skin smear and .