tailieunhanh - Báo cáo y học: "A pilot study of a new test to predict extubation failure"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: A pilot study of a new test to predict extubation failure. | Available online http content 13 2 R56 Research A pilot study of a new test to predict extubation failure José F Solsona1 Yolanda Diaz1 Antonia Vazquez1 Maria Pilar Gracia1 Ana Zapatero1 and Jaume Marrugat2 1ICU Hospital de Mar Paseo Maritimo 25-29 Barcelona 08003 Spain 2Institut Municipal d Investigacio Medica C Aiguader 80 Barcelona 08003 Spain Corresponding author José F Solsona 13713@ Received 10 Dec 2008 Revisions requested 20 Jan 2009 Revisions received 19 Feb 2009 Accepted 14 Apr 2009 Published 14 Apr 2009 Critical Care 2009 13 R56 doi cc7783 This article is online at http content 13 2 R56 2009 Solsona et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction To determine whether subjecting patients to 100 ml of additional dead space after a 1 20-minute weaning trial could predict readiness for extubation. Methods This was a prospective non-randomised pilot study in an intensive care unit at a university hospital with 14 beds. It included all non-tracheostomised patients with improvement of the underlying cause of acute respiratory failure and those with no need for vasoactive or sedative drugs were eligible. Patients fulfilling the Consensus Conference on Weaning extubation criteria after 120 minutes spontaneous breathing n 152 were included. To the endotracheal tube 100 cc dead space was added for 30 minutes. Patients tolerating the test were extubated those not tolerating it received six hours of supplementary ventilation before extubation. The measurements taken and main results were arterial pressure heart rate respiratory rate oxygen saturation end-tidal carbon dioxide and signs of respiratory insufficiency were recorded every five .