tailieunhanh - Báo cáo y học: "Management dilemma; a woman with cystic fibrosis and severe lung disease presenting with colonic carcinoma: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Management dilemma; a woman with cystic fibrosis and severe lung disease presenting with colonic carcinoma: a case report | Journal of Medical Case Reports BioMed Central Open Access Case report Management dilemma a woman with cystic fibrosis and severe lung disease presenting with colonic carcinoma a case report Andrea N Lees and David W Reid Address Department of Respiratory Medicine Royal Hobart Hospital 48 Liverpool Street Hobart Tasmania 7000 Australia Email Andrea N Lees - andreal@ David W Reid - decreid@ Corresponding author Published 15 December 2008 Received 22 January 2008 Journal of Medical Case Reports 2008 2 384 doi l752-l947-2-384 Accepted 15 December 2008 This article is available from http content 2 l 384 2008 Lees and Reid licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction There are increasing reports of bowel cancer in cystic fibrosis suggesting a possible causal link. Individuals with cystic fibrosis who have advanced lung disease present a high operative risk limiting curative treatment options in early bowel malignancy. Case presentation We describe a 4l-year-old Caucasian woman with cystic fibrosis and severe lung disease who had been considered for lung transplantation who presented with rectal bleeding and was found to have a Stage I adenocarcinoma of the sigmoid colon. After considerable discussion as to the operative risks she underwent a laparoscopic resection and remains relatively well l year postoperatively with no recurrence. Conclusion We discuss the complexity of the management decisions for cystic fibrosis patients with severe lung disease and early stage colonic malignancy particularly in the context of potential need for lung transplantation. The case demonstrates that cystic fibrosis patients with very severe lung function .