tailieunhanh - Báo cáo y học: "Bilateral dystonia in type 1 diabetes: a case report"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Bilateral dystonia in type 1 diabetes: a case report | Journal of Medical Case Reports BioMed Central Case report Bilateral dystonia in type 1 diabetes a case report Akihiro Yasuhara Jun Wada and Hirofumi Makino Open Access Address Department of Medicine and Clinical Science Okayama University Graduate School of Medicine 2-5-1 Shikata-cho Okayama 700-8558 Japan Email Akihiro Yasuhara - akihiroyasuhara@ Jun Wada - junwada@ Hirofumi Makino - makino@ Corresponding author Published 18 November 2008 Received 18 April 2008 _ r- n Anno J. .IA I lo mri lorn in Accepted 18 November 2008 Journal of Medical Case Reports 2008 2 352 doi 186 1752-1947-2-352 This article is available from http content 2 1 352 2008 Yasuhara et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Introduction Diabetic hemichorea-hemiballismus is a rare complication of type 2 diabetes. Here we report a case with type 1 diabetes with hemichorea and bilateral dystonia manifested as hyperglycemia-induced involuntary movement. Case presentation A 62-year-old Japanese women with body weight loss of 30 kg during the past year developed symptoms of thirst polydipsia and polyuria. She also presented with hemichorea and bilateral dystonia for 5 days and extremely high plasma glucose 774 mg dl hemoglobin A1c and glycated albumin 100 with ketosis. Based on the presence of glutamic acid decarboxylase antibodies 18 000 U ml normal U ml low daily urinary excretion of C-peptide pg ketosis and human leucocyte antigen typing DR-4 we diagnosed type 1 diabetes mellitus. We treated the patient with a continuous intravenous regular insulin infusion and medication with haloperidol and dystonia completely disappeared within 3 days. .