tailieunhanh - Báo cáo y học: "Efficacy of positive end-expiratory pressure titration after the alveolar recruitment manoeuvre in patients with acute respiratory distress syndrom"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Efficacy of positive end-expiratory pressure titration after the alveolar recruitment manoeuvre in patients with acute respiratory distress syndrome. | Available online http content 13 1 R22 Research Efficacy of positive end-expiratory pressure titration after the alveolar recruitment manoeuvre in patients with acute respiratory distress syndrome Jin Won Huh1 Hoon Jung1 Hye Sook Choi2 Sang-Bum Hong3 Chae-Man Lim3 and Younsuck Koh3 Department of Pulmonary and Critical Care Medicine Inje University Ilsan Paik Hospital Daehwa-dong Goyang-si 411-706 Korea department of Pulmonary and Critical Care Medicine Dongguk University College of Medicine Seokjang-dong Gyeongju-si 780-714 Korea department of Pulmonary and Critical Care Medicine Asan Medical Center University of Ulsan College of Medicine 388-1 Pungnap-dong Seoul 138-736 Korea Corresponding author Younsuck Koh yskoh@ Received 3 Nov 2008 Revisions requested 10 Dec 2008 Revisions received 14 Jan 2009 Accepted 24 Feb 2009 Published 24 Feb 2009 Critical Care 2009 13 R22 doi cc7725 This article is online at http content 13 1 R22 2009 Huh et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction In acute respiratory distress syndrome ARDS adequate positive end-expiratory pressure PEEP may decrease ventilator-induced lung injury by minimising overinflation and cyclic recruitment-derecruitment of the lung. We evaluated whether setting the PEEP using decremental PEEP titration after an alveolar recruitment manoeuvre ARM affects the clinical outcome in patients with ARDS. Methods Fifty-seven patients with early ARDS were randomly assigned to a group given decremental PEEP titration following ARM or a table-based PEEP control group. PEEP and inspired fraction of oxygen FiO2 in the control group were set according to the table-based combinations of FiO2 and PEEP