tailieunhanh - Báo cáo y học: "In silico evidence for the species-specific conservation of mosquito retroposons: implications as a molecular biomarker"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: In silico evidence for the species-specific conservation of mosquito retroposons: implications as a molecular biomarker. | Theoretical Biology and Medical Modelling BioMed Central Research In silico evidence for the species-specific conservation of mosquito retroposons implications as a molecular biomarker Wilson Byarugaba1 2 3 Henry Kajumbula1 4 and Misaki Wayengera 1 3 5 Address 1Restrizymes Biotherapeutics U LTD PO Box 16606 Kampala Uganda 2Dept of Postgraduate Studies and Research Kampala International University Western Campus PO Box 71 Ishaka Uganda 3Division of Molecular Pathology Dept of Pathology School of Biomedical Sciences College of Health Sciences Makerere University PO Box 7072 Kampala Uganda 4Division of Molecular Biology Dept of Medical Microbiology School of Biomedical Sciences College of Health Sciences Makerere University PO Box 7072 Kampala Uganda and 5Dept of Immunology and Microbiology Kampala International University Western Campus PO Box 71 Ishaka Uganda Email Wilson Byarugaba - wbyarugaba@ Henry Kajumbula - jumbic@ Misaki Wayengera - wmisaki@ Corresponding author Open Access Published 29 July 2009 Received 31 March 2009 Theoretical Biology and Medical Modelling 2009 6 14 doi 1742-4682-6-14 Accepted 29 July 2009 This article is available from http content 6 1 14 2009 Byarugaba et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Mosquitoes are the transmissive vectors for several infectious pathogens that affect man. However the control of mosquitoes through insecticide and pesticide spraying has proved difficult in the past. We hypothesized that by virtue of their reported vertical inheritance among mosquitoes group II introns - a class of small coding ribonucleic acids scRNAs - may form a potential species-specific biomarker. Structurally .