tailieunhanh - Báo cáo y học: "Determinants of weaning success in patients with prolonged mechanical ventilation"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Determinants of weaning success in patients with prolonged mechanical ventilation. | Available online http content 13 3 R97 Research Determinants of weaning success in patients with prolonged mechanical ventilation Annalisa Carlucci1 Piero Ceriana1 Georgios Prinianakis2 Francesco Fanfulla1 Roberto Colombo3 and Stefano Nava1 Respiratory Intensive Care Unit Fondazione S. Maugeri IRCCS Via Maugeri 10 Pavia 27100 Italy 2Department of Intensive Care Medicine University Hospital of Heraklion Stavrakia Heraklion 71110 Crete Greece 3Service of Clinical Engineering Fondazione S. Maugeri IRCCS Via Maugeri 10 Pavia 27100 Italy Corresponding author Annalisa Carlucci Received 15 Feb 2009 Revisions requested 31 Mar 2009 Revisions received 11 May 2009 Accepted 23 Jun 2009 Published 23 Jun 2009 Critical Care 2009 13 R97 doi cc7927 This article is online at http content 13 3 R97 2009 Carlucci et al. licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Open Access Abstract Introduction Physiological determinants of weaning success and failure are usually studied in ventilator-supported patients comparing those who failed a trial of spontaneous breathing with those who tolerated such a trial and were successfully extubated. A major limitation of these studies was that the two groups may be not comparable concerning the severity of the underlying disease and the presence of comorbidities. In this physiological study we assessed the determinants of weaning success in patients acting as their own control once they are eventually liberated from the ventilator. Methods In 30 stable tracheotomised ventilator-dependent patients admitted to a weaning center inside a respiratory intensive care unit we recorded the breathing pattern respiratory mechanics inspiratory muscle function .