tailieunhanh - Báo cáo y học: "Parosteal osteosarcoma mimicking osteochondroma: A radio-histologic approach on two cases"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Parosteal osteosarcoma mimicking osteochondroma: A radio-histologic approach on two cases. | PH CLINICAL SARCOMA RESEARCH Parosteal osteosarcoma mimicking osteochondroma A radio-histologic approach on two cases Papathanassiou et al. O Centra I Papathanassiou et al. Clinical Sarcoma Research 2011 1 2 http content W2 25 July 2011 Papathanassiou et al. Clinical Sarcoma Research 2011 1 2 http content 1 1 2 CLINICAL SARCOMA RESEARCH RESEARCH Open Access Parosteal osteosarcoma mimicking osteochondroma A radio-histologic approach on two cases Zafiria G Papathanassiou 1 Marco Alberghini2 Philippe Thiesse3 Marco Gambarotti2 Giuseppe Bianchi4 Cristina Tranfaglia5 and Daniel Vanel1 Abstract Objective Parosteal osteosarcoma is a well-differentiated variant of osteosarcoma that affects the surface of the bone. The imaging pattern is very typical. We report two cases mimicking an osteochondroma radiologically and histologically and propose an explanation. Material The review of 86 parosteal osteosarcomas of bone revealed this atypical pattern only once. A consultation case was received in the same time and added to ours. Patients were 28 years old and 56 years old females. Imaging studies included two radiographs two CTscans one MRI examination and one bone scan and the results were compared to histology. Results On imaging both lesions presented as ossified lobulated masses attached with a broad base to the underlying cortex. No radiolucent cleft separated the masses and the host bone and cortex continuity between the mass and the femur was seen with medullary communication. The marrow of the mass had a different density and intensity compared to normal marrow. So there were features of an osteochondroma cortex and medullary continuity and of a parosteal osteosarcoma ossified marrow . Pathological assessment on the final specimen confirmed the presence of low-grade parosteal osteosarcomas after an erroneous diagnosis of osteochondroma on the initial biopsy. Conclusions Parosteal osteosarcoma can be rarely