tailieunhanh - Báo cáo y học: "Effects of triptolide from Radix Tripterygium wilfordii (Leigongteng) on cartilage cytokines and transcription fact"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài:Effects of triptolide from Radix Tripterygium wilfordii (Leigongteng) on cartilage cytokines and transcription fact. | Chinese Medicine BioMed Central Research Effects of triptolide from Radix Tripterygium wilfordii Leigongteng on cartilage cytokines and transcription factor NF-kB a study on induced arthritis in rats Cheng Xiao1 2 Jing Zhou2 Yinghui He3 Hongwei Jia2 Linhua Zhao2 Ning Zhao2 and Aiping Lu 2 4 Address institute of Clinical Medicine Research China-Japan Friendship Hospital Beijing 100029 PR China institute of Basic Theory China Academy of Traditional Chinese Medicine Beijing 100700 PR China 3National Pharmaceutical Engineering Centre for Herbal Preparations Jiangxi University of Traditional Chinese Medicine Nanchang Jiangxi 330006 PR China and 4E-institutes of Shanghai Municipal Education Commission Shanghai University of Traditional Chinese Medicine Shanghai 201203 PR China Email ChengXiao-xc2002812@ JingZhou - zhoujing@ Yinghui He - yingying402@ Hongwei Jia - jiahongwei@ Linhua Zhao - melonzhao@ Ning Zhao - zhaoning@ Aiping Lu -lap64067611@ Corresponding author Open Access Published 2 July 2009 Chinese Medicine 2009 4 13 doi 1749-8546-4-1 3 Received 20 January 2009 Accepted 2 July 2009 This article is available from http content 4 1 13 2009 Xiao et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Triptolide an active compound of Radix Tripterygium wilfordii is immunosuppressive cartilage protective and anti-inflammatory both in human and animal studies of various inflammatory and autoimmune diseases including rheumatoid arthritis but its therapeutic mechanism remains unclear. The aim of this study is to investigate the effects of triptolide on cartilage cytokines in the CIA model. Methods Sprague Dawley rats were immunized with .

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