tailieunhanh - Báo cáo y học: " Recent advances in the investigation of curcuminoids"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Recent advances in the investigation of curcuminoids. | Chinese Medicine BioMed Central Open Access Review Recent advances in the investigation of curcuminoids Hideji Itokawa Qian Shi Toshiyuki Akiyama Susan L Morris-Natschke and Kuo-Hsiung Lee Address Natural Products Research Laboratories School of Pharmacy University of North Carolina Chapel Hill North Carolina 27599-7360 USA Email Hideji Itokawa - itokawah@ Qian Shi - qshi1 @ Toshiyuki Akiyama - akiyama@ Susan L Morris-Natschke - susan_natschke@ Kuo-Hsiung Lee - khlee@ Corresponding author Published 17 September 2008 Received 22 May 2008 Accepted 17 September 2008 Chinese Medicine 2008 3 11 doi l749-8546-3-ll This article is available from http content 3 l l l 2008 Itokawa et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract More than 30 Curcuma species Zingiberaceae are found in Asia where the rhizomes of these plants are used as both food and medicine such as in traditional Chinese medicine. The plants are usually aromatic and carminative and are used to treat indigestion hepatitis jaundice diabetes atherosclerosis and bacterial infections. Among the Curcuma species C. longa C. aromatica and C. xanthorrhiza are popular. The main constituents of Curcuma species are curcuminoids and bisabolane-type sesquiterpenes. Curcumin is the most important constituent among natural curcuminoids found in these plants. Published research has described the biological effects and chemistry of curcumin. Curcumin derivatives have been evaluated for bioactivity and structureactivity relationships SAR . In this article we review the literature between 1976 and mid-2008 on the anti-inflammatory anti-oxidant anti-HIV chemopreventive and anti-prostate cancer .