tailieunhanh - Báo cáo y học: "Pharmacological effects of Radix Angelica Sinensis (Danggui) on cerebral infarction"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Pharmacological effects of Radix Angelica Sinensis (Danggui) on cerebral infarction. | Wu and Hsieh Chinese Medicine 2011 6 32 http content 6 1 32 CHINESE MEDICINE REVIEW Open Access Pharmacological effects of Radix Angelica Sinensis Danggui on cerebral infarction Yi-Chian Wu1 and Ching-Liang Hsieh1 2 3 Abstract Radix Angelica Sinensis the dried root of Angelica sinensis Danggui is a herb used in Chinese medicine to enrich blood promote blood circulation and modulate the immune system. It is also used to treat chronic constipation of the elderly and debilitated as well as menstrual disorders. Research has demonstrated that Danggui and its active ingredients as anti-arthrosclerotic anti-hypertensive antioxidant anti-inflammatory agents which would limit platelet aggregation are effective in reducing the size of cerebral infarction and improving neurological deficit scores. Background Danggui the dried root of Angelica Sinensis Radix Angelica Sinensis is a commonly used Chinese medicinal herb to enrich blood promote blood circulation and treat blood deficiency pattern and menstrual disorders such as dysmenorrhea and irregular menstrual cycle 1 . Wilasrusmee et al. 2 reported that Danggui 105 pg ml plays an immunostimulatory role in mitogen-stimulated murine lymphocytes in vitro. Angelan a purified polysaccharide component of Angelica nakai thought to improve immune function increases the expression of cytokines in splenocytes as Angelan enhances and the production of interleukin-6 IL-6 and interferon-g IFN-y of activated macrophages helper T cells and natural killer cells 3 . The chemical constituents of the Danggui extract are classified into essential oil and water soluble parts including lipid compounds phenolic compounds carbohydrates organic acids and other constituents 4 . The most active ingredients are polysaccharides Z-Ligustilide 3-butylidene-4 5-dihydrophthalide and ferulic acid 4-hydroxy-3-methoxycinnamicacid 1 . This article aims to provide an overview of the pharmacological effects of Danggui in reducing the size of .