tailieunhanh - Báo cáo y học: "Does improvement management of atopic dermatitis influence the appearance of respiratory allergic diseases? A follow-up study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Does improvement management of atopic dermatitis influence the appearance of respiratory allergic diseases? A follow-up study. | Ricci et al. Clinical and Molecular Allergy 2010 8 8 http content 8 1 8 RESEARCH CMA CLINICAL AND MOLECULAR ALLERGY Open Access Does improvement management of atopic dermatitis influence the appearance of respiratory allergic diseases A follow-up study Giampaolo Ricci 1 Annalisa Patrizi2 Arianna Giannetti1 Arianna Dondi1 Barbara Bendandi1 and Massimo Masi1 Abstract Background Atopic dermatitis AD is often the prelude to allergic diseases. The aim of this study was 1 to evaluate if an integrated management regime could bring about a change in the evolution of the disease in comparison to the results of a previous study 2 to determine whether the refinement of allergic investigations allowed to identify more promptly the risk factors of evolution into respiratory allergic diseases. Methods The study included 176 children affected by AD and previously evaluated between 1993 and 2002 at the age of 9-16 months who underwent a telephonic interview by means of a semi-structured pre-formed questionnaire after a mean follow-up time of 8 years. According to the SCORAD at first evaluation children had mild AD in 23 of cases moderate in 62 severe in 15 . Results AD disappeared in 92 cases 52 asthma appeared in 30 17 and rhinoconjunctivitis in 48 27 . The factors significantly related to the appearance of asthma were sensitization to food allergens with sIgE 2 KU L cow s milk and hen s egg P to inhalant allergens with sIgE KU L P . Logistic regression analysis showed that inhalant sensitization was positively related to the occurrence of asthma OR . While AD showed similar rates of disappearance to those of our previous study the incidence of asthma was reduced at the same follow-up time from 29 to 15 P and the incidence of rhinoconjunctivitis from 35 to 24 P . Conclusion Comparing the results with those of the previous study integrated management of AD does not seem to influence its natural course. Nevertheless .