tailieunhanh - báo cáo khoa học: " Can context justify an ethical double standard for clinical research in developing countries?"

Tuyển tập báo cáo các nghiên cứu khoa học quốc tế ngành y học dành cho các bạn tham khảo đề tài: Can context justify an ethical double standard for clinical research in developing countries? | Globalization and Health BioMed Central Debate Open Access Can context justify an ethical double standard for clinical research in developing countries Megan Landes Address London School of Hygiene and Tropical Medicine 1 Keppel Street London WC1E 7HT UK Email Megan Landes - Corresponding author Published 26 July 2005 Received 18 February 2005 Globalization and Health 2005 1 11 doi 1744-8603-1-11 Accepted 26 July 2005 This article is available from http content 1 1 1 1 2005 Landes licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background The design of clinical research deserves special caution so as to safeguard the rights of participating individuals. While the international community has agreed on ethical standards for the design of research these frameworks still remain open to interpretation revision and debate. Recently a breach in the consensus of how to apply these ethical standards to research in developing countries has occurred notably beginning with the 1994 placebo-controlled trials to reduce maternal to child transmission of HIV-1 in Africa Asia and the Caribbean. The design of these trials sparked intense debate with the inclusion of a placebo-control group despite the existence of a gold standard and trial supporters grounded their justifications of the trial design on the context of scarcity in resource-poor settings. Discussion These contextual apologetics are arguably an ethical loophole inherent in current bioethical methodology. However this convenient appropriation of contextual analysis simply fails to acknowledge the underpinnings of feminist ethical analysis upon which it must stand. A more rigorous analysis of the political .