tailieunhanh - Báo cáo y học: " Distribution of hepatitis C virus genotypes in patients infected by different sources and its correlation with clinical and virological parameters: a preliminary study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: Distribution of hepatitis C virus genotypes in patients infected by different sources and its correlation with clinical and virological parameters: a preliminary study. | Comparative Hepatology BioMed Central Research Distribution of hepatitis C virus genotypes in patients infected by different sources and its correlation with clinical and virological parameters a preliminary study Ali Kabir 1 4 Seyed-Moayed Alavian1 2 and Hussein Keyvani1 3 Open Access Address Tehran Hepatitis Center Tehran Iran 2Department of Gastroenterology Baqyiatallah University of Medical Sciences Iran 3Department of Virology Iran University of Medical Sciences Tehran Iran and 4Nikan Health Researchers Institute Tehran Iran Email Ali Kabir - aikabir@ Seyed-Moayed Alavian - editor@ Hussein Keyvani - manager@ Corresponding author Published 02 October 2006 Comparative Hepatology 2006 5 4 doi l476-5926-5-4 Received 18 January 2005 Accepted 02 October 2006 This article is available from http content 5 l 4 2006 Kabir et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Information about genotypes and associated risk factors in hepatitis C virus HCV infected patients in Iran is limited. The aim of this study was to identify the HCV genotypes and associated risk factors in a group of HCV infected patients from Iran. Results Genotyping analysis was performed in l56 patients with positive anti-HCV and HCV-RNA. Patients were questioned concerning documented risk factors. Genotypes l and 3 were found in 87 and 45 patients respectively. The most frequent HCV subtype was la followed by 3a and lb . There was no statistically significant difference between the risk factors analyzed and the acquisition of HCV infection. We further found that l8 40 and l7 patients that were intravenous drug users IVDU