tailieunhanh - Báo cáo y học: " The establishment and characterization of the first canine hepatocellular carcinoma cell line, which resembles human oncogenic expression patterns"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học Critical Care giúp cho các bạn có thêm kiến thức về ngành y học đề tài: The establishment and characterization of the first canine hepatocellular carcinoma cell line, which resembles human oncogenic expression patterns. | Comparative Hepatology BioMed Central Research Open Access The establishment and characterization of the first canine hepatocellular carcinoma cell line which resembles human oncogenic expression patterns Sacha Y Boomkens1 Bart Spee1 Jooske IJzer2 Ronald Kisjes2 Herman F Egberink3 Ted SGAM van den Ingh2 Jan Rothuizen1 and Louis C Penning 1 Address Department of Clinical Sciences of Companion Animals Faculty of Veterinary Medicine Utrecht University Yalelaan 8 . Box 80154 3508 TD Utrecht The Netherlands 2Department of Pathobiology Division of Pathology Faculty of Veterinary Medicine Utrecht University The Netherlands and 3Department of Infectious Diseases and Immunology Division of Virology Faculty of Veterinary Medicine Utrecht University The Netherlands Email Sacha Y Boomkens - sacha_raymond@ Bart Spee - Jooske IJzer - Ronald Kisjes - Herman F Egberink - Ted SGAM van den Ingh - Jan Rothuizen - Louis C Penning - Corresponding author Published 26 November 2004 Received 13 August 2004 Accepted 26 November 2004 Comparative Hepatology 2004 3 9 doi l476-5926-3-9 r This article is available from http content 3 1 9 2004 Boomkens et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract Background Hepatocellular carcinoma HCC is one of the most worldwide frequent primary carcinomas resulting in the death of many cirrhotic patients. Unfortunately the molecular mechanisms of this cancer are not well understood therefore we need a good model system to study HCC. The dog is recognized as a promising model for human medical .