tailieunhanh - Báo cáo y học: "Aggressive HIV-1?"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Aggressive HIV-1? | Retrovirology BioMed Central Commentary Aggressive HIV-1 Ben Berkhout Anthony de Ronde and Lia van der Hoek Open Access Address Department of Human Retrovirology Academic Medical Center University of Amsterdam Meibergdreef 15 1105 AZ Amsterdam the Netherlands Email Ben Berkhout - Anthony de Ronde - ronde@ Lia van der Hoek - Corresponding author Published 28 February 2005 Received 25 February 2005 Accepted 28 February 2005 Retrovirology 2005 2 13 doi 1742-4690-2-1 3 This article is available from http content 2 1 13 2005 Berkhout et al licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License http licenses by which permits unrestricted use distribution and reproduction in any medium provided the original work is properly cited. Abstract New York City health officials announced on February II 2005 that a patient rapidly developed full-blown AIDS shortly after being diagnosed with a rare drug-resistant strain of HIV-1. The New York City Department of Health issued an alert to all hospitals and doctors and a press conference was held to announce the emergence of an aggressive HIV- 1 strain that may be difficult to treat and that appears to trigger rapid progression to AIDS. Is the panic justified The two phenomena of rapid disease progression and multi-drug resistance which are combined in the aggressive HIV-1 strain are not unique. HIV-1 causes a persistent infection and this virus is generally not a fast killer. Within the Amsterdam Cohort Studies on HIV-AIDS it takes on average years from the time a person is first infected with HIV-1 for AIDS to develop and another 17 months from AIDS to death 1 . However the length of the incubation period varies from 2 months to more than 20 years. Cases where it takes much shorter are not uncommon rapid-progressors and likewise there is a .