tailieunhanh - Báo cáo y học: "Increased mortality associated with HTLV-II infection in blood donors: a prospective cohort study"

Tuyển tập các báo cáo nghiên cứu về y học được đăng trên tạp chí y học quốc tế cung cấp cho các bạn kiến thức về ngành y đề tài: Increased mortality associated with HTLV-II infection in blood donors: a prospective cohort study | Retrovirology Research Increased mortality associated with HTLV-II infection in blood donors a prospective cohort study Jennie R Orland1 Baoguang Wang2 David J Wright2 Catharie C Nass3 George Garratty4 James W Smith5 Bruce Newman6 Donna M Smith2 Edward L Murphy 1 and For the HOST Investigators Address University of California San Francisco and Blood Systems Research Institute San Francisco CA USA 2Westat Rockville MD USA 3American Red Cross Blood Services Greater Chesapeake and Potomac Region Baltimore MD USA 4American Red Cross Blood Services Southern California Region Los Angeles CA USA 5Sylvan N. Goldman Center Oklahoma Blood Institute Oklahoma City OK USA and 6American Red Cross Blood Services Southeastern Michigan Region Detroit MI USA Email Jennie R Orland - orland@ Baoguang Wang - wangb@ David J Wright - Catharie C Nass - Catharie@ George Garratty - garratty@ James W Smith - jsmith@ Bruce Newman - newmanb@ Donna M Smith - smithd2@ Edward L Murphy - murphy@ For the HOST Investigators - murphy@ Corresponding author Published 24 March 2004 Received 04 March 2004 Accepted 24 March 2004 Retrovirology 2004 1 4 This article is available from http content 1 1 4 2004 Orland et al licensee BioMed Central Ltd. This is an Open Access article verbatim copying and redistribution of this article are permitted in all media for any purpose provided this notice is preserved along with the article s original URL. Abstract Background HTLV-I is associated with adult T-cell leukemia and both HTLV-I and -II are associated with HTLV-associated myelopathy tropical spastic paraparesis HAM TSP . Several published reports suggest that HTLV-I may lead to decreased survival but HTLV-II has not previously been associated with mortality. Results We examined deaths among 138 HTLV-I 358 HTLV-II and 759 uninfected controls enrolled in a